This article is from the WeChat public account: span> Nature-Research span> , the title picture comes from: Figure Worm span> p>
p>
Apart from the cells that make up our body, there are trillions of microbes in our body. These microorganisms include not only beneficial bacteria that help the intestines digest, but also bacteria that parasitize our skin, mouth, and vagina. In addition to bacteria, there are various viruses, fungi and archaea in the human body. strong> p>
p>
When did microbial colonization begin? Most scientists believe that we were exposed to bacteria for the first time at birth, and that before birth, the fetus developed in a sterile environment; however, some recent studies have found that placenta and amniotic fluid surrounding the fetus contain bacterial DNA. Bacteria are also present in the first fetus after birth. p>
p>
p>
Can this prove that we symbiotic with bacteria before we are born? It is possible, but many scientists believe that these results are caused by pollution. p>
p>
The controversy surrounding this issue continues, and regardless of the final answer, everyone agrees that the first major colonization occurred during and shortly after delivery. p>
p>
The babies born with birth will get some bacteria from the mother when they pass through the birth canal.In the air, contact with surrounding objects and people, get more microorganisms. p>
p>
As she grows up, many factors will affect the composition of the microbiome, including diet, whether to take antibiotics or other drugs, how many people have been in contact, whether to keep pets, where she lives, and possibly her Genetic composition. p>
p>
Children who grew up in the countryside are surrounded by animals and dust. The microbes in these children are different from children who grow up in the city. If children are not exposed to a wide variety of microbes, they seem more likely to develop autoimmune diseases and allergies, such as asthma and eczema. This theory is called the Hygiene Hypothesis, and it proves in one way how our microbiota affects our health throughout life. strong> p>
p>
In adulthood, the number of microorganisms in our body is at least as high as the number of human cells, and our physiological functions depend on these communities. strong> For example, they can help us resist harmful bacteria and help us digest food. Microorganisms break down food and produce molecules called metabolites. These metabolites reach the various tissues of the body with the blood circulation, affecting our metabolism. p>
p>
Diversity of the intestinal flora is beneficial to metabolic health, and insufficient diversity may lead to inflammatory bowel disease, obesity and type 2 diabetes. Even studies have shown that microbial metabolites can affect the brain and our mental health. As we age, our microbiota continues to change. strong> Studies have shown that the gut microbiota of older people is different from that of young adults, which may cause age-related changes in the immune system and brain function. p>
p>
In the future, we need to further understand how the various microorganisms that symbiotic with us can promote and affect our physical and mental health. We need to better understand why microorganisms differ from person to person and how these differences affect our biological characteristics. It is particularly important that we study more about the microbes of non-white populations and populations in other parts of the world. p>
p>
There is no doubt about it: without these microbes, there would be no us. p>
p>
This article is from the WeChat public account: span> Nature-Research span> p>