Problem description: My mother was 57 years old and was admitted to the hospital with cholecystitis. I did an endoscopy and found that I was suffering from a differentiated duodenal papillary adenocarcinoma. I just had surgery, do I need chemotherapy next?
Question date:2021-04-26
Patient information:Age: 57 years old Gender: Female
Question analysis: Papillary adenocarcinoma of the duodenum, more than 20 days after the poorly differentiated operation. After the operation, lymph node involvement, vascular invasion, resection margins, and pathological staging were not described. It is planned to clarify the further diagnosis and treatment plan.
Guide and suggestion: 1) Duodenal papillary adenocarcinoma, the pathological diagnosis is clear, it is recommended to continue to go to the general surgery or oncology department. 2) For poorly differentiated adenocarcinoma in the intestine, whether chemotherapy is required should be determined according to whether there is lymph node metastasis or vascular invasion after surgical resection; if there is no positive metastasis, the stage is earlier, and regular gastroscopy review is sufficient. 3) If surgical resection is incomplete or recurrence, you can consider whether you need targeted therapy based on the results of genetic testing, such as VEGF inhibitor bevacizumab; EGFR inhibitor panitumumab; and PD-1 inhibitor Pabo Livzumab and Nivolumab and other treatments.
Recommendations are for reference only. If the problem is serious, please go to the hospital for detailed examination