Production | Tiger Sniff Technology Group

Author | Shi Xuxu

Cover from the Internet

February 7, the 6th day of Tang Moumou’s suspected case of new coronary pneumonia in Ziyang, Sichuan. She started to cough and had flaky shadows in her lungs. During the quarantine, she underwent eight nucleic acid tests one after the other and all were negative. Strangely enough, from the perspective of lung imaging and clinical symptoms, its characterization has not diminished.

On February 24th, on the 23rd day of the quarantine, she did the ninth nucleic acid test. The result was positive and she was finally diagnosed.

Tang Moumou’s experience is not an individual case. Frequent “false negative” cases are questionable, and nucleic acid testing, which has always been regarded as the gold standard for the diagnosis of new coronary pneumonia, does not seem to be so smart.

Every time it takes 4 to 6 hours for the detection of New Coronavirus nucleic acid. In the case of a large number of suspected patients and asymptomatic infections still to be investigated, the diagnosis efficiency is particularly low, and the entire process has added more infections to medical staff. risk.

Absolutely, antibody tests that can efficiently perform complementary diagnostics were born.

Recently, the China Drug Administration approved two colloidal gold antibody detection reagents from two companies, namely Wanfu Biological New Coronavirus (2019-nCoV) Antibody Detection Kit (colloidal gold method) and Innotec Biotechnology 2019-new coronavirus IgM / IgG combined detection kit (colloidal gold method).

According to the introduction, both products can realize the qualitative detection of neogranulovirus IgM / IgG antibodies in human blood in vitro, and the results can be obtained in 15 minutes.

And compared to nucleic acid detection, antibody detection can advance the diagnostic time.

“These two kits can detect IgM antibodies on the 7th day of the infection or the 3rd day of the disease, which is very helpful for the further diagnosis of the patient.” Zhong Nanshan said.

20 times faster detection speed

A complete set of nucleic acid detection procedures mainly includes the steps of sampling, preservation, sample inactivation, nucleic acid extraction, reagent reaction, and fluorescent PCR nucleic acid detection.