More sweet and less unexpected.
Eat one slice for a month.
According to Pear Video, on December 4, Lyndra Biopharmaceuticals in the United States announced the development of a monthly contraceptive pill for women and has completed animal experiments in vivo. Although the long-acting contraceptives currently on the market have a high contraceptive rate, they need to be taken daily. Occasionally forgetting to take them will reduce the contraceptive effect.
Obviously, this monthly pill makes things a little easier.
Once swallowed, the tablet will stay in the stomach for several weeks, slowly release contraceptive hormones, and when it completes its work, it will disintegrate and be excreted from the body.
The working principle of this tablet has also been reported previously , a supramolecular elastomer gel designed by the team Contains polyacryl 6-aminocaproic acid and methacrylic acid-ethyl acrylate copolymer, which is particularly soft and flexible. It can be compressed and folded into capsules for easy swallowing by patients. It is small enough to pass safely through the esophagus and Stretch in the stomach into a ring with a diameter of more than 3cm, even larger can reach 6cm.
Because this material is pH-sensitive, it can survive the harsh acidic environment of the stomach, resist digestion of the gastric juice, and slowly release the drug it loads until it encounters a pH near the middle after entering the small intestine The sexual environment begins to dissolve. This completely eliminates the risk of intestinal obstruction.
Screenshot from Pear Video
Lyndra is a cutting-edge biopharmaceutical company founded in Massachusetts, USA. The founder of Robert Langer is a professor at MIT, and his team hopes to use ultra-long-acting sustained-release pharmaceutical preparations to allow patients to Take medication monthly to eliminate the burden of frequent daily medication and reduce the cost of care.
In addition to evolving contraceptives from daily to weekly and even monthly, Lyndra is also advancing drug research and development in the treatment of Alzheimer’s disease, AIDS, opioid use disorders, and schizophrenia. < strong> The point is to take one pill for longer.
The official website shows that for schizophrenia, Lyndra has submitted an application to the FDA toConducted clinical trials on patients taking risperidone (a drug used to treat schizophrenia) once a week; in the treatment of Alzheimer’s disease, Lyndra cooperated with Ailjian to develop weekly oral capsules AIDS, Lyndra and Gilead Sciences have collaborated to develop an ultra-long-term oral HIV treatment plan that allows patients to take the medicine once a week.
In July of this year, Lyndra also received a $ 13 million B + round of funding from the Gates Foundation. That’s why once the monthly contraceptive pill was released, it wore a celebrity aura in the media. However, when it will be on the market, it has to go through clinical trials and approvals. In January of this year, Lyndra received $ 55 million in Series B financing, which was mainly used to expand the phase II clinical trials of ultra-long-acting oral drugs.
From Tianyancha
However, more anticipation than female monthly contraceptives is still Risug, a male contraceptive developed and being approved in India —— “Reversible inhibition of sperm under guidance (Risug)”, known as a needle for 13 years . But have to wait, if the Risug approval goes smoothly, it will take two years at the earliest to experience.
Of course, in terms of contraception, whether it is for men or women, injections or medications, it is sweeter and less unexpected for modern people.
(Source: unsplash)