This article is from the public number: Tech Daily (ID: kjrbwx) , author: Science and Technology Daily reporter Ye
“In terms of animal models, China has successfully constructed a smallAnimal models such as mice and monkeys provide basic conditions for the safety and effectiveness evaluation of drugs and vaccines. “Not long ago, the State Council’s joint defense and control mechanism revealed at a press conference.
Recently, under the guidance of Academician Zhong Nanshan, the research team of Professor Zhao Jincun of the State Key Laboratory of Respiratory Diseases of Guangzhou Medical University jointly with the State Key Laboratory of Biosafety Testing of Guangzhou Customs Technology Center > (P3 laboratory) , Guangzhou Institute of Biomedicine and Health, Chinese Academy of Sciences, and Guangdong Experimental Animal Monitoring Institute successfully established the world’s first non-transgenic mouse model of new coronavirus pneumonia.
At the same time, at a news conference on prevention and control of the epidemic held on March 12, Guangdong Province, the Guangdong Provincial Department of Science and Technology revealed that the Guangdong Provincial Laboratory of Regenerative Medicine and Health has established a humanized ACE2 mouse model of the new crown virus receptor .
What is the significance of successfully constructing an animal model of disease for conquering new coronary pneumonia? The reporter interviewed relevant experts.
Why build an animal model of disease? What’s the point?
The so-called human disease animal model refers to animals with simulated human disease performance established in various medical scientific research.
“Because of ethics, feelings, risks, and other factors, it is determined that we cannot use humans to conduct dangerous and harmful experiments. Animals and humans have an evolutionary relationship and there are similarities. You can use this to reason and judge whether What will happen in the human body? “Said Huang Ren, deputy director of the Chinese Society of Experimental Animals. Therefore, appropriate laboratory animals are generally used to simulate human diseases to study the occurrence and development of human diseases, find treatment methods, and verify the effects of drug treatment. As well as side effects.
Huang Ren especially emphasized that animal models of human diseases are actually human substitutes and human victims. In scientific research, it is indispensable. He said: “An animal model of disease can reproduce or reveal the universality and specificity of things, which is the true meaning of the model in science. And it can reduce experimental risks and save costs. Once the animal model is successfully developed, Widely used and can be promoted. “
Technology Daily (ID: kjrbwx) , author: Science and Technology Daily reporter Ye